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Dr. Daniel H. Fine is currently a Professor and Chairman of the Department of Oral Biology and Director of the Center for Oral Infectious Diseases. He received his Bachelor of Science degree from Queens College, his DMD from the University of Pennsylvania in 1965 and his Certificate in Periodontology in 1967 from New York University. He served on the dental faculties of the University of Pittsburgh (1967-1970) and the Columbia University School of Dental and Oral Surgery (1971-1994) before coming to the New Jersey Dental School in mid-1994 as Director of the Dental Research Center. Dr. Fine's research focuses on host/parasite interactions in periodontal disease with a special emphasis on molecular genetics related to virulence of actinobacillus actinomycetemcomitans. His group also investigates genetic susceptibility of individuals to juvenile periodontitis. In addition, Dr. Fine's laboratory participates in studies of biofilm development and methods that would interfere with development. RECENT PUBLICATIONS Fine, DH., Velliyagounder, K., Furgang D., Kaplan, JB. The Actinobacillus actinomycetemcomitans Autotransporter Adhesin Aae Exhibits Specificity for Buccal Epithelial Cells from Humans and Old World Primates. Infection and Immunity. p. 1947-1953, 2005. Kaplan, JB., Meyenhoff, MF., Fine, DH. Biofilm growth and detachment of Actinobacillus actinomycetemcomitans. Journal of Bacteriology. Vol185, 1399-1404, 2003. Kaplan, JB., Meyenoff, MF., and Fine, DH. Biofilm growth and detachment of Actinobacillus Actinomycetemcomitans. Journal of Bacteriology. Vol. 185, No. 4, 1399-1404, 2003. Schreiner, Helen, C., Sinatra, Kathy, Kaplan, Jeffrey, B., Furgang, David, Kachlany, Scott, C., Planet, Paul, J., Perez, Brenda, A., Figurski, David, H., Fine Daniel, H. Tight adherence genes of Actinobacillus actinomycetemcomitans are required for virulence in a rat model. PNAS. Vol. 100, No. 12 7295-7300. 2003. Kablian Velliyagounder, Jeffrey B. Kaplan, David Furgang, Diana Legarda, Gill Diamond, Ruth E. Parkin, and Daniel H. Fine. One of Two Human Lactoferrin Variants Exhibits Increased Activation Activities and Is Associated with Localized Juvenile Periodontitis. Infection and Immunity. Nov. 2003, p. 6141-6147 2003. Kaplan, JB., and Fine, DH. Biofilm dispersal of Neiserria subflava and other phylogenetically diverse oral bacteria. Applied Environment Microbiol. Vol. 68, 4943-4950, 2002. |
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