|
|
|
|
|
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
Daniel Kadouri received a Bachelor of Science degree in Biology and Agriculture from the Hebrew University of Jerusalem in 1996, a Master of Science degree in Virology in 1998 and a Ph.D. in Microbiology from the same institution in 2003. He received his postdoctoral training in the Department of Microbiology and Immunology at Dartmouth Medical School , Hanover, N.H. Daniel joined the Department of Oral Biology at New Jersey Dental School in 2006. Kadouri’s lab focuses on the interaction of biofilms and predatory prokaryotes. Most bacteria found in natural or industrial settings persist in complex microbial communities attached to surfaces or associated with interfaces (biofilms). Recently, there has been a renewed interest in the use of biological control agents against biofilms. These agents include the use of invertebrates and protozoa to reduce biofilms by means of grazing and the use of bacteriophages. In our work we are using bacteria from the genera Bdellovibrio and Micavibrio in order to reduce biofilms with the long term goal of harnessing the potential of these organisms in controlling biofilms both in medical and industrial settings, developing novel biological control strategies, and employing these biological systems as means of enhancing classical biofilm control techniques. We are currently developing new methods that will allow us to isolate proteins which have antibacterial properties that could be used as therapeutic agents, as well as investigating the role of these proteins in predator-host-biofilm interactions. In another study we are investigating the role of biofilms in oral infectious diseases. Periodontal disease is a chronic biofilm-based disease that occurs in more than 35% of the adult population in the U.S. Tanerella forsythensis is an anaerobe that resides within the biofilm community in the subgingival crevice of the oral cavity and is regarded as a major contributory agent in periodontal disease. The focus of our research is to study the relationship between biofilm development and pathogenicity.RECENT PUBLICATIONS Kadouri, D., Venzon, N, and O'Toole, G. A. Vulnerability of Pathogenic Biofilms to Micavibrio aeruginosavorus. Applied and Environmental Microbiology. (in press) Merritt, J. H., Kadouri, D., and O'Toole, G. A. 2005. Growing and analyzing Static Biofilms. In Current Protocols in Microbiology, John Wiley & Sons. NJ, Vol. 1, 1B.1.1-17. Kadouri, D. and O'Toole, G. A. 2005. Susceptibility of biofilms to Bdellovibrio bacteriovorus attack. Applied and Environmental Microbiology. 71:4044-4051. Kadouri, D., Jurkevitch, E., Okon, Y. and Castro-Sowinski, S. 2005. Ecological and agricultural significance of bacterial polyhydroxyalkanoates. Critical Reviews in Microbiology. 31:55-67. Edelshtein, Z., Kadouri, D., Jurkevitch, E., Vander Broke, A., Vanderleyden, J. and Okon, Y. 2003. Charactrization of genes involved in Poly beta-hydroxybutyrate metabolism in Azospirillum brasilense. Symbiosis. 34:157-170. Kadouri, D., Jurkevitch, E. and Okon, Y. 2003. Poly beta-hydroxybutyrate depolymerase (PhaZ) in Azospirillum brasilense and characterization of a phaZ mutant. Archives of Microbiology. 180:309-318. Kadouri, D., Jurkevitch, E. and Okon, Y. 2003. Involvement of the reserve material poly-beta-hydroxybutyrate in Azospirillum brasilense stress endurance and root colonization. Applied and Environmental Microbiology. 69:3244-3250. Kadouri, D., Burdman, S., Jurkevitch, E. and Okon, Y. 2002.Identification and isolation of genes involved in poly b -hydroxybutyrate (PHB) biosynthesis in Azospirillumbrasilense and characterization of a phbC mutant. Applied and Environmental Microbiology. 68:2943-2949. |
|
||||||||||||
