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Jeffrey Kaplan received a Bachelor of Science degree in Biology from the University of Illinois at Chicago in 1980 and a Ph.D. in Molecular Biology from the same institution in 1985. He received postdoctoral training in the Department of Microbiology at the Albert Einstein College of Medicine, Bronx, N.Y., and in the Department of Microbiology at Columbia University, College of Physicians and Surgeons, New York, N.Y. Kaplan worked for 10 years in the Oncology Department at Wyeth Pharmaceuticlas, Pearl River, N.Y., before joining the Department of Oral Biology at New Jersey Dental School in 1999.
Kaplan's lab is studying the detachment and dispersal of bacterial cells from biofilms with an emphasis on the gram-negative periodontal pathogen Actinobacillus actinomycetemcomitans. Kaplan’s lab is currently funded by a grant from the NIH.
RECENT PUBLICATIONS
KAPLAN JB, Meyenhofer MF, Fine DH. 2003. Biofilm growth and detachment of Actinobacillus actinomycetemcomitans. Journal of Bacteriology 185:1399-1404.
KAPLAN JB, Chandran R, Ramasubbu N, Fine DH. 2003. Detachment of Actinobacillus actinomycetemcomitans biofilm cells by an endogenous b-hexosaminidase activity. Journal of Bacteriology 185:4692-4698.
KAPLAN JB, Chandran R, Velliyagounder K., Fine DH, Ramasubbu N. 2004. Enzymatic detachment of Staphylococcus epidermidis biofilms. Antimicrobial Agents and Chemotherapy 48:2633-2636.
KAPLAN JB, Velliyagounder K, Chandran R, Rohde H, Mack D, Knobloch JKM, Ramasubbu N. 2004. Genes involved in the synthesis and degradation of matrix polysaccharide in Actinobacillus actinomycetemcomitans and Actinobacillus pleuropneumoniae biofilms. Journal of Bacteriology 185:8213-8220.
Ramasubbu N, Thomas L, Ragunath, C, KAPLAN JB. 2005. Structural analysis of dispersin B, a biofilm-releasing glycoside hydrolase from the periodontopathogen Actinobacillus actinomycetemcomitans. Journal of Molecular Biology 349:475-486.
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